How to use; Size 10 grams and 50 grams: 1 spoon (1 gram) per 100 liters of water.Size 250 grams and size 1 kilogram: 1 spoon (5 grams) per 500 liters of water. Instructions for use: After 48 hours of use, reapply (no need to change the water). Apply the medicine again once a week for 4 weeks in a row to completely eliminate worms and parasites in every stage of their life cycle.