Used for CKD (chronic kidney disease) and renal failure- serum creatinine level beyond 1.4 mg/dl in dogs & 1.6 mg/dl in cats. Directions for use; Body weight of Dog- 8-12 kg ½Tablet Twice a day, Body weight of Dog 13-25 kg 1Tablet Twice a day, Body weight of Dog 26-45 kg 2Tablet Twice a day, Body weight of Dog >45 kg 3Tablet Twice a day.